Meshroom S V2 – Standard ITX Layout
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- CPU: Ryzen 9 7950X3D
- GPU: RTX 4090
- Cooling: 280 AIO
- PSU: SFX-L
The Ultimate SFF Fitment Center. From ITX to ATX.
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The ITX layout is the reference configuration for the Meshroom S V2, designed around a Mini-ITX motherboard (170 × 170 mm) with full GPU compatibility and flexible front and rear mounting options.

The Meshroom S V2 supports front, rear, and SFF GPU mounting. Maximum GPU length and thickness depend on tray position and whether additional feet are installed.
| Tray mode | Without additional feet | With additional feet |
|---|---|---|
| 3-slot (tray position) | 314 × 120 × 61 mm | 335 × 120 × 61 mm |
| 4-slot (tray position) | 314 × 120 × 76 mm | 335 × 120 × 76 mm |
| Tray mode | Without additional feet | With additional feet |
|---|---|---|
| 3-slot (tray position) | 332 × 153 × 63 mm | 353 × 153 × 61 mm |
| 4-slot (tray position) | 332 × 153 × 82 mm | 353 × 153 × 82 mm |
* Recommended configuration for most users.
| GPU type | Reference size |
|---|---|
| SFF GPU | 239 × 160 × 63 mm |
Note: Use 90° DP/HDMI connectors when GPU I/O clearance to the bottom frame is tight.
| GPU position | Supported riser cable length |
|---|---|
| Front GPU | 145 mm or 200 mm |
| Rear GPU | 145 mm or 200 mm |
| SFF GPU | 200 mm or 220–270 mm |
Cable length selection depends on routing preference and GPU position. Excessively long cables may impact cable management and airflow.
| GPU tray mode | Maximum CPU cooler height |
|---|---|
| 3-slot mode | 74 mm |
| 4-slot mode | 54 mm |
CPU cooler clearance is affected by GPU tray position. Verify cooler height including fan and top cover.
| Mounting position | Supported radiator size | Dimensional limits | Notes |
|---|---|---|---|
| Front | 240 mm / 280 mm |
Max total thickness (radiator + fan): 63 mm Max radiator width: 144 mm |
Fully supported |
| Rear | 240 mm / 280 mm |
Max total thickness (radiator + fan): 63 mm Max radiator width: 144 mm |
Depends on GPU width |
The maximum thickness of 63 mm refers to the combined thickness of the radiator and fan assembly.
Mounting the fan facing outward increases the total radiator assembly width to a maximum of 154 mm.
Rear AIO compatibility depends on GPU thickness and tubing clearance. Clearance verification is required before installation.
| PSU type | Supported configuration |
|---|---|
| SFX or ATX (≤ 150 mm) |
Supports 55 mm thickness downward-tubing AIO assembly. Radiator must be oriented facing outward. |
| ATX (160 mm width) | Supports 55 mm thickness upward-tubing AIO assembly. |
| ATX (170 mm width) | Fan assembly supported. |
PSU dimensions and tubing direction directly affect AIO compatibility. Verify total assembly thickness before installation.
| Drive type | Maximum supported | Mounting locations |
|---|---|---|
| 3.5" HDD | Up to 4 drives |
Rear (behind PSU): 2 Front of motherboard tray: 2 |
| 2.5" SSD | Up to 8 drives |
Top: 2 Bottom: 2 Rear (behind PSU): 4 |
The quantities listed above represent all available mounting locations within the ITX layout.
Actual usable drive count depends on whether GPU, PSU, or AIO components occupy shared mounting space.
Storage compatibility may vary based on system configuration. Clearance verification is required when combining multiple components.
The diagrams below illustrate GPU length limits for different mounting positions in the ITX layout.
Meshroom S V2 ATX motherboard compatibility depends primarily on GPU mounting position. The following tables define verified component limits for each supported GPU layout.

Meshroom S V2 | ATX Motherboard Front GPU Layout – Component Compatibility
| Component | Supported Specification | Notes / Constraints |
|---|---|---|
| GPU Position | Front-mounted GPU (Recommended) | This is the primary and recommended GPU layout for ATX motherboards |
| Riser Cable | 270–320 mm | Longer cables may complicate routing and airflow |
| GPU (3-slot mode) | Up to 335 × 120 × 61 mm | GPU width is a critical factor; minor width overages may require an expansion bracket |
| GPU (4-slot mode) | Up to 334 × 120 × 76 mm | GPU thickness directly impacts airflow and cable clearance |
| Additional GPU Notes | — | GPUs longer than 332 mm require additional aluminum feet for bottom clearance |
| CPU Cooler |
• 3-slot: up to 74 mm • 4-slot: up to 54 mm |
Clearance changes with GPU slot configuration |
| PSU | SFX only | SFX PSU is mandatory for front GPU layout in ATX configuration |
| AIO Cooling | 240 mm AIO only | Maximum radiator + fan thickness: 53 mm |
Meshroom S V2 | ATX Motherboard Rear GPU Layout – Component Compatibility
| Component | Supported Specification | Notes / Constraints |
|---|---|---|
| GPU Position | Rear-mounted GPU | Requires careful cooling and airflow planning |
| Riser Cable | 385–440 mm | Long riser cables require controlled routing to avoid signal degradation |
| GPU (3-slot mode) | Up to 353 × 153 × 63 mm | GPU height and airflow clearance are critical |
| GPU (4-slot mode) | Up to 353 × 153 × 82 mm | 4-slot GPUs require additional airflow planning |
| Additional GPU Notes | — | GPUs longer than 332 mm require aluminum feet to raise chassis clearance |
| CPU Cooler |
• 3-slot: up to 74 mm • 4-slot: up to 54 mm |
Cooler height is reduced in 4-slot GPU mode |
| PSU | SFX only | ATX PSU is not supported in rear GPU layout |
Meshroom S V2 | ATX Motherboard SFF GPU Layout – Component Compatibility
| Component | Supported Specification | Notes / Constraints |
|---|---|---|
| GPU Type | SFF GPU only | Standard full-length GPUs are not supported in this layout |
| Riser Cable | 440 mm | Long cable required due to alternate routing path |
| CPU Cooler |
• 3-slot: up to 74 mm • 4-slot: up to 54 mm |
Same height limits as other ATX layouts |
| PSU | SFX or ATX | This is the only ATX layout supporting full-size ATX PSUs |
ATX Layout – GPU and PSU Structural Reference
The builds below showcase real-world Meshroom S V2 ATX layout installations shared by the community, demonstrating achievable configurations under actual use conditions.

Meshroom S V2 Standard ATX Layout

Meshroom S V2 Standard ATX White
CPU: i7 13700K
GPU: Colorful iGame RTX 4070 Ultra Z
MB: Colorful CVN Z790D5 ARK FROZEN V20
Cooler: Asus ROG Strix 240
PSU: SEASONIC SPX750

Meshroom S V2 ATX MB+ DIY Wood
GPU: Inno3d RTX 5060ti
MB: GIGABYTE Z690 AORUS PRO
Cooling: Deepcool LM240 aio
PSU: Seasonic focus SPX750 PSU

Meshroom S V2 ATX MB + ATX PSU
CPU: AMD Ryzen 7 7800X3D
GPU: Zotac SFF GPU
MB: ATX
CPU Cooler
Power Supply: ATX PSU
The following table outlines compatibility details specific to the Meshroom S V2 when using a micro-ATX (mATX) motherboard. All other component constraints follow the same rules defined for the ATX motherboard layout.

Meshroom S V2 | mATX Motherboard Layout – Component Compatibility
| Component | Supported Configuration | Notes / Constraints |
|---|---|---|
| Motherboard | micro-ATX (mATX) | Larger footprint than ITX; internal layout constraints follow ATX motherboard rules |
| GPU Position – Front | Supported | Recommended primary configuration for mATX motherboard layout |
| Riser Cable (Front GPU) | 175–320 mm | Length selection depends on GPU height and internal cable routing path |
| GPU Position – Rear | Supported | Requires additional airflow and cooling system planning |
| Riser Cable (Rear GPU) | 300–440 mm | Extended cable length required for rear GPU routing |
| GPU Position – SFF | Supported (SFF GPU only) | Limited to short-length SFF GPUs due to motherboard clearance |
| Riser Cable (SFF GPU) | 340–440 mm | Longer riser cable required due to internal routing distance |
| Power Supply | SFX;ATX PSU only works with SFF GPU | Same PSU restrictions as ATX motherboard layout |
| CPU Cooler Height | 74 mm (3-slot) / 54 mm (4-slot) | GPU slot mode directly affects maximum CPU cooler height |
| AIO Support | 240 mm only | Radiator and fan thickness limits identical to ATX layout |
Custom loop water cooling configurations shown below are advanced, DIY reference builds.They are not covered by standard compatibility guarantees and require individual planning, measurement, and execution.Please refer to the official Meshroom S V2 Basic and Advanced User guide and detailed guides before attempting a custom loop build.
Custom loop water cooling configurations shown below are advanced, DIY reference builds.
They are not covered by standard compatibility guarantees and require individual planning, measurement, and execution.
Please refer to the official Meshroom S V2 Basic and Advanced User guide and detailed guides before attempting a custom loop build.

The following builds are shared by experienced users and showcase custom loop implementations in Meshroom S V2.
Results may vary depending on component selection and installation technique.

Meshroom S V2 Water Cooling

Meshroom S V2 Standard ATX White

Meshroom S V2 Dual 280 AIO

Meshroom S V2 Peacock
Quick Compatibility Summary
• ITX motherboards provide the widest configuration flexibility across all GPU, AIO and PSU options.
• ATX and mATX motherboards require careful GPU position planning and are limited to SFX power supplies in most layouts.
• GPU length alone does not determine compatibility — thickness, height, and airflow clearance are critical.
• 4-slot GPUs require additional planning for airflow, cable routing, and internal clearance.
• Modular power supplies significantly improve build success in compact layouts.
Which Layout Should You Choose?
• Choose ITX layout if you want maximum GPU flexibility and simplified cable routing.
• Choose ATX layout if you need full-size motherboard support and are willing to plan GPU positioning carefully.
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